Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532888 | 0.79 | BDKRB1 (0.39) | CCKBRALDH1A1MAPTPKMHPGD | |
| SCHEMBL8773971 | 0.74 | CCKBR (0.45) | CCKBRALDH1A1CCKARTRPA1BDKRB1 | |
| SCHEMBL8773965 | 0.74 | CCKBR (0.45) | CCKBRALDH1A1CCKARTRPA1BDKRB1 | |
| SCHEMBL8537963 | 0.72 | ALDH1A1 (0.48) | CCKBRALDH1A1PKMHSD17B10CCKAR | |
| SCHEMBL8537959 | 0.72 | ALDH1A1 (0.48) | CCKBRALDH1A1PKMHSD17B10CCKAR | |
| SCHEMBL8773950 | 0.70 | CCKBR (0.42) | CCKBRALDH1A1HSD17B10CCKARTRPA1 | |
| SCHEMBL8536369 | 0.69 | ALDH1A1 (0.42) | CCKBRALDH1A1MAPTPKMHPGD | |
| SCHEMBL8536373 | 0.69 | ALDH1A1 (0.42) | CCKBRALDH1A1MAPTPKMHPGD | |
| SCHEMBL8537982 | 0.68 | ALDH1A1 (0.41) | CCKBRALDH1A1MAPTPKMHPGD | |
| SCHEMBL8537988 | 0.68 | ALDH1A1 (0.41) | CCKBRALDH1A1MAPTPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |