Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533255 | 0.78 | CES2 (0.38) | CES2CES1ALDH1A1MAPTPOLB | |
| SCHEMBL11227120 | 0.77 | HTT (0.36) | CES2CES1ALDH1A1MAPTPOLB | |
| SCHEMBL3082114 | 0.76 | CES2 (0.39) | CES2CES1ALDH1A1MAPTPOLB | |
| SCHEMBL10586210 | 0.75 | CES2 (0.38) | CES2CES1ALDH1A1MAPTPOLB | |
| SCHEMBL6512450 | 0.74 | CES1 (0.37) | CES2CES1ALDH1A1MAPTPOLB | |
| SCHEMBL3468482 | 0.70 | TSHR (0.35) | CES2CES1ALDH1A1LMNAMAPT | |
| SCHEMBL6903621 | 0.70 | CES2 (0.33) | CES2CES1ALDH1A1LMNAMAPT | |
| SCHEMBL136598 | 0.70 | MAPT (0.41) | CES2CES1ALDH1A1MAPTPOLB | |
| SCHEMBL337965 | 0.69 | TSHR (0.38) | CES2CES1ALDH1A1MAPTPOLB | |
| SCHEMBL4035521 | 0.67 | ALDH1A1 (0.39) | CES2CES1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822221-A2 | Novel light stabilisers based on sterically hindered amines | Clariant GmbH (DE) | 1998-02-04 | — | — | EP | disclosed |