SCHEMBL337965

SCHEMBL337965

CNC1(NC)C=CC(C(=O)c2ccccc2)C=C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALOX15 P16050 3/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
HBB P68871 1/20 0.38
EPHX1 P07099 1/20 0.37
CES1 P23141 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
SRC P12931 1/20 0.36
CES2 O00748 2/20 0.35
ALDH1A1 P00352 2/20 0.35
DAO P14920 1/20 0.35
NAPRT Q6XQN6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10585531 0.82 TSHR (0.41) TSHRALOX15MAPTHTTHBB
SCHEMBL2470208 0.81 EPHX1 (0.43) TSHRALOX15MAPTHTTHBB
SCHEMBL811694 0.81 CES1 (0.41) TSHRALOX15MAPTHTTHBB
SCHEMBL10702666 0.80 SRC (0.39) TSHRALOX15MAPTHTTHBB
SCHEMBL5677227 0.80 CES2 (0.41) TSHRALOX15MAPTHTTHBB
SCHEMBL136598 0.79 MAPT (0.41) TSHRALOX15MAPTHTTHBB
SCHEMBL3082114 0.79 CES2 (0.39) TSHRALOX15MAPTHTTHBB
SCHEMBL7420069 0.79 HTT (0.40) TSHRALOX15MAPTHTTHBB
SCHEMBL157513 0.79 RAB9A (0.38) TSHRALOX15MAPTHTTHBB
SCHEMBL9640021 0.79 CES1 (0.39) TSHRALOX15MAPTHTTHBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021183667-A1 SWELLABLE PHOTOPOLYMERIZED HYDROGELS FOR EXPANSION MICROSCOPY THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2021-09-16 WO claimed
CN-109721861-A A kind of Photosensitive self-crosslinking EPDM waterproof rolled sheet and preparation method thereof 四川省宏源防水工程有限公司 2019-05-07 CN claimed
CN-106279737-A A kind of PET protection film with excellent anti-scratch performance 苏州柯创电子材料有限公司 2017-01-04 CN claimed
CN-106188599-A A kind of high-performance double-layer PET film 苏州柯创电子材料有限公司 2016-12-07 CN claimed
CN-102827332-B Ultraviolet-cured transparent halogen-free flame-retardant unsaturated polyester and preparation method thereof UNIV SOUTH CHINA TECH 2014-09-10 CN claimed
CN-102827332-A Ultraviolet-cured transparent halogen-free flame-retardant unsaturated polyester and preparation method thereof UNIV SOUTH CHINA TECH 2012-12-19 CN claimed
EP-1932882-B1 HARDENABLE COMPOSITION AND OPTICAL MEMBER MAKING USE OF THE SAME HOYA CORP (JP) 2011-09-21 EP claimed
US-20090318581-A1 HARDENABLE COMPOSITION AND OPTICAL MEMBER MAKING USE OF THE SAME HOYA CORPORATION (JP) 2009-12-24 US claimed
EP-1932882-A1 HARDENABLE COMPOSITION AND OPTICAL MEMBER MAKING USE OF THE SAME Hoya Corporation (JP) 2008-06-18 EP claimed
US-20070197756-A1 Curable Composition And Optical Member Using Same HOYA CORPORATION (JP) 2007-08-23 US claimed
EP-1728804-A1 CURABLE COMPOSITION AND OPTICAL MEMBER USING SAME Hoya Corporation (JP) 2006-12-06 EP claimed
JP-60208303-A None JP disclosed
US-12637573-B2 Antifouling coating composition CHUGOKU MARINE PAINTS, LTD. (JP) 2026-05-26 US disclosed
US-12434265-B2 Coating method TOKUYAMA CORPORATION (JP) 2025-10-07 US disclosed
US-20240400855-A1 THERMOSETTING RESIN COMPOSITION, CURED PRODUCT, AND PRINTED WIRING BOARD TAIYO HOLDINGS CO., LTD. (JP) 2024-12-05 US disclosed
JP-S60208303-A PHOTOSENSITIVE RESIN COMPOSITION NITTO ELECTRIC IND CO LTD 1985-10-19 JP disclosed
US-4414275-A ETCHING, POLYVINYL FORMAL, PHOTOPOLYMERIZABLE ACRYLATE, RELEASE COATING LOCTITE (IRELAND) LIMITED (IE) 1983-11-08 US disclosed
EP-0081972-A1 Two-part, two-tier cure adhesive composition LOCTITE CORPORATION (US) 1983-06-22 EP disclosed
EP-0011918-A2 Polymerisable compositions, derived coatings and other polymerised products IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-06-11 EP disclosed
EP-0010897-A2 Polymerisable compositions, derived coatings and other polymerised products IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637573-B2 Antifouling coating composition COL1A1, COL2A1, HBS1L TSHR 2286/4885ALOX15 2257/4885MAPT 3202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.