SCHEMBL6512450

SCHEMBL6512450

O=C(c1ccccc1)C1C=CC(F)([N+](=O)[O-])C=C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.37
CES2 O00748 2/20 0.37
MAPT P10636 2/20 0.34
ALOX15 P16050 1/20 0.34
HTT P42858 1/20 0.34
HBB P68871 1/20 0.34
EPHX1 P07099 2/20 0.33
POLB P06746 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
MITF O75030 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
TP53 P04637 1/20 0.33
PRMT1 Q99873 1/20 0.33
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3082114 0.84 CES2 (0.39) CES1CES2MAPTALOX15HTT
SCHEMBL8533255 0.83 CES2 (0.38) CES1CES2MAPTALOX15HTT
SCHEMBL10586210 0.83 CES2 (0.38) CES1CES2MAPTALOX15HTT
SCHEMBL993045 0.80 CES1 (0.45) CES1CES2MAPTALOX15HTT
SCHEMBL4959086 0.78 CES1 (0.39) CES1CES2MAPTALOX15HTT
SCHEMBL3468482 0.78 TSHR (0.35) CES1CES2MAPTALOX15HTT
SCHEMBL337965 0.77 TSHR (0.38) CES1CES2MAPTALOX15HTT
SCHEMBL7420069 0.77 HTT (0.40) CES1CES2MAPTALOX15HTT
SCHEMBL7430909 0.77 CES1 (0.38) CES1CES2MAPTALOX15HTT
SCHEMBL7423415 0.77 CES1 (0.38) CES1CES2MAPTALOX15HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215152-A1 POLYARYLETHERKETONE WITH WIDE MOLECULAR WEIGHT DISTRIBUTION AND PREPARATION METHOD THEREFOR JILIN JOINATURE POLYMER CO., LTD. (CN) 2025-07-03 US disclosed
CN-120157870-A Polyether-ether-ketone resin with adjustable molecular weight distribution, and synthetic method and application thereof 吉林省中研高分子材料股份有限公司 2025-06-17 CN disclosed
CN-120157871-A Sodium salt and potassium salt composition, low dielectric constant polyether-ether-ketone and synthesis method and application thereof 吉林省中研高分子材料股份有限公司 2025-06-17 CN disclosed
EP-4495166-A1 POLYARYLETHERKETONE WITH WIDE MOLECULAR WEIGHT DISTRIBUTION AND PREPARATION METHOD THEREFOR Jilin Joinature Polymer Co., Ltd. (CN) 2025-01-22 EP disclosed
WO-2023202616-A1 POLYARYLETHERKETONE WITH WIDE MOLECULAR WEIGHT DISTRIBUTION AND PREPARATION METHOD THEREFOR 吉林省中研高分子材料股份有限公司 2023-10-26 WO disclosed
CN-115636933-B Polyaryletherketone with wide molecular weight distribution and preparation method thereof 吉林省中研高分子材料股份有限公司 2023-08-04 CN disclosed
CN-115636933-A9 Polyaryletherketone with wide molecular weight distribution and preparation method thereof 吉林省中研高分子材料股份有限公司 2023-04-25 CN disclosed
WO-2005037839-A1 NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF ENTOMED (FR) 2005-04-28 WO disclosed
EP-0970033-A1 PROCESS FOR PREPARATION OF AROMATIC COMPOUNDS VICTREX MANUFACTURING LIMITED (GB) 2000-01-12 EP disclosed
WO-1998040338-A1 PROCESS FOR PREPARATION OF AROMATIC COMPOUNDS VICTREX MANUFACTURING LIMITED (GB) 1998-09-17 WO disclosed