Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535820 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL27533957 | 0.74 | BCL2L1 (0.40) | ALDH1A1SMN1; SMN2MAPTHAO1BCL2L1 | |
| SCHEMBL14966754 | 0.73 | HDAC8 (0.51) | ALDH1A1SMN1; SMN2MAPTHAO1LMNA | |
| SCHEMBL11754496 | 0.72 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTHAO1BCL2L1 | |
| SCHEMBL8535121 | 0.70 | ADRB2 (0.45) | ALDH1A1MAPTHTTPOLBKDM4E | |
| SCHEMBL27832625 | 0.70 | HAO1 (0.64) | ALDH1A1SMN1; SMN2MAPTHAO1BCL2L1 | |
| SCHEMBL9788805 | 0.70 | HAO1 (0.64) | ALDH1A1SMN1; SMN2MAPTHAO1BCL2L1 | |
| SCHEMBL2550435 | 0.70 | HAO1 (0.64) | ALDH1A1SMN1; SMN2MAPTHAO1BCL2L1 | |
| SCHEMBL1278464 | 0.70 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTHAO1BCL2L1 | |
| SCHEMBL30089520 | 0.70 | HAO1 (0.68) | ALDH1A1SMN1; SMN2MAPTHAO1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |