Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16042348 | 0.86 | RXFP1 (0.44) | ALDH1A1KDM4EHTTKMT2AMEN1 | |
| SCHEMBL27498315 | 0.84 | SLC7A5 (0.47) | ALDH1A1KMT2AMEN1NPC1SLC7A5 | |
| SCHEMBL16043976 | 0.79 | HSD11B1 (0.39) | ALDH1A1MAPTKDM4EHTTKMT2A | |
| SCHEMBL8536465 | 0.77 | ERCC5 (0.42) | ADRB2ADRB1ADRB3CTNNB1WNT3A | |
| SCHEMBL8535820 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EHTTKMT2A | |
| SCHEMBL16042292 | 0.76 | KMT2A (0.37) | ADRB2ADRB1ADRB3ALDH1A1KMT2A | |
| SCHEMBL8014554 | 0.75 | SMN1; SMN2 (0.48) | ADRB2ADRB1ADRB3CTNNB1WNT3A | |
| SCHEMBL16042409 | 0.73 | HTT (0.48) | ALDH1A1MAPTKDM4EHTTKMT2A | |
| SCHEMBL24952178 | 0.72 | NPSR1 (0.48) | CTNNB1WNT3AALDH1A1MAPTHTT | |
| SCHEMBL31223766 | 0.72 | NPSR1 (0.48) | CTNNB1WNT3AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |