Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536624 | 0.83 | ALDH1A1 (0.55) | ALDH1A1LMNARECQLHSD17B10ALOX15 | |
| SCHEMBL8533950 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNATDP1MAPTHDAC1 | |
| SCHEMBL8535121 | 0.77 | ADRB2 (0.45) | ALDH1A1TDP1MAPTNPC1NPSR1 | |
| SCHEMBL16042348 | 0.76 | RXFP1 (0.44) | ALDH1A1LMNAMAPK1TDP1NPC1 | |
| SCHEMBL8536465 | 0.74 | ERCC5 (0.42) | ALDH1A1NPC1RAB9ATHRBTSHR | |
| SCHEMBL16043976 | 0.74 | HSD11B1 (0.39) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL27498315 | 0.74 | SLC7A5 (0.47) | ALDH1A1NPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16042409 | 0.73 | HTT (0.48) | ALDH1A1HSD17B10MAPTNPC1RAB9A | |
| SCHEMBL16042292 | 0.73 | KMT2A (0.37) | ALDH1A1LMNATHRBKMT2ASMN1; SMN2 | |
| SCHEMBL11014128 | 0.73 | MAPT (0.58) | ALDH1A1LMNARECQLHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |