Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.43 |
| ▸ | F2 | P00734 | 7/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531077 | 0.85 | PRSS1 (0.43) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8429101 | 0.79 | PTGER4 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8430846 | 0.75 | F10 (0.41) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8530521 | 0.70 | ENPP2 (0.47) | — | |
| SCHEMBL23229045 | 0.67 | PKM (0.47) | — | |
| Hydrochloric Acid SCHEMBL3303778 | 0.67 | F10 (0.64) | F10F2 | |
| SCHEMBL8531524 | 0.67 | ENPP2 (0.39) | — | |
| SCHEMBL1505615 | 0.65 | F10 (0.65) | F10F2 | |
| SCHEMBL2390130 | 0.65 | CYP4F2 (0.51) | HPGD | |
| SCHEMBL6366473 | 0.65 | DHODH (0.44) | F10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |