Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | MPO | P05164 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535301 | 0.80 | DRD2 (0.44) | SLC6A3DRD2SLC6A4HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8535321 | 0.79 | DRD2 (0.43) | SLC6A3DRD2SLC6A4HTR2AHTR2C | |
| SCHEMBL8536618 | 0.77 | HTR2C (0.43) | SLC6A3MPODRD2SLC6A4HTR2A | |
| SCHEMBL8531818 | 0.68 | HRH3 (0.45) | SLC6A3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL14454756 | 0.67 | HTR1A (0.71) | SLC6A3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL8536585 | 0.67 | HRH3 (0.44) | DRD2HTR2AHTR2CHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL8535833 | 0.67 | HRH3 (0.44) | SLC6A3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL8583613 | 0.66 | HTR1A (0.40) | SLC6A3DRD2HTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL8536660 | 0.66 | HTR1A (0.69) | SLC6A3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL8531503 | 0.66 | HTR2A (0.41) | DRD2HTR2AHTR2CHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847159-A | 1- ω-(3,4-dihydro-2-naphthalenyl)alkyl!-cyclic amine derivatives, process for preparing the same, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |