Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8535321 | 0.99 | DRD2 (0.43) | DRD2HTR2AHTR2BHTR2CHTR1A | |
| SCHEMBL8534629 | 0.80 | SLC6A3 (0.40) | DRD2HTR2AHTR2BHTR2CHTR1A | |
| SCHEMBL14454756 | 0.76 | HTR1A (0.71) | DRD2HTR2AHTR2BHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL8536660 | 0.75 | HTR1A (0.69) | DRD2HTR2AHTR2BHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL8536805 | 0.74 | HTR1A (0.68) | DRD2HTR2AHTR2BHTR2CHTR1A | |
| SCHEMBL8536618 | 0.74 | HTR2C (0.43) | DRD2HTR2AHTR2BHTR2CHTR1A | |
| SCHEMBL8583613 | 0.69 | HTR1A (0.40) | DRD2HTR2AHTR2BHTR2CHTR1A | |
| SCHEMBL8430318 | 0.68 | SIGMAR1 (0.44) | DRD2HTR2AHTR2BHTR2CHTR1A | |
| SCHEMBL12073194 | 0.65 | ALDH1A1 (0.68) | HTR2ASLC6A3SIGMAR1HRH3ALDH1A1 | |
| SCHEMBL8531818 | 0.65 | HRH3 (0.45) | DRD2HTR2AHTR2BHTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847159-A | 1- ω-(3,4-dihydro-2-naphthalenyl)alkyl!-cyclic amine derivatives, process for preparing the same, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | claimed |
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | claimed |
| JP-10175862-A | — | — | None | — | — | JP | disclosed |
| US-5847159-A | 1- ω-(3,4-dihydro-2-naphthalenyl)alkyl!-cyclic amine derivatives, process for preparing the same, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| JP-H10175862-A | PHARMACEUTICAL COMPOSED OF 1-(OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL) CYCLIC AMINE DERIVATIVE | DAINIPPON PHARMACEUT CO LTD | 1998-06-30 | — | — | JP | disclosed |
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |