Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13885864 | 0.82 | ALOX5 (0.55) | ALOX5TYR | |
| SCHEMBL4547674 | 0.77 | HSPA5 (0.50) | — | |
| Bromide SCHEMBL28018020 | 0.76 | HSPA5 (0.48) | — | |
| SCHEMBL13885884 | 0.73 | AKR1B1 (0.35) | — | |
| SCHEMBL3631479 | 0.72 | MAOB (0.36) | ALOX5BCL2BCL2L1SLC6A4 | |
| SCHEMBL13885858 | 0.71 | EGFR (0.42) | ALOX5TYR | |
| SCHEMBL8315943 | 0.71 | CA1 (0.51) | ALOX5 | |
| SCHEMBL4117115 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL16406322 | 0.70 | APP (0.44) | APP | |
| SCHEMBL28694881 | 0.70 | TAAR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732328-B1 | Aromatic heterocyclic compounds, pharmaceutical and cosmetic compositions containing them and their uses | CIRD GALDERMA (FR) | 1998-09-09 | — | — | EP | disclosed |
| EP-0732328-A1 | Aromatic heterocyclic compounds, pharmaceutical and cosmetic compositions containing them and their uses | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1996-09-18 | — | — | EP | disclosed |