Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13885858 | 0.82 | EGFR (0.42) | CA9CA14MEN1KMT2AHPGD | |
| SCHEMBL6635805 | 0.79 | ALDH1A1 (0.50) | CA9MEN1KMT2AANO1HPGD | |
| SCHEMBL4547674 | 0.77 | HSPA5 (0.50) | CA9HIF1AHSD17B10MPOKDM4E | |
| Bromide SCHEMBL28018020 | 0.76 | HSPA5 (0.48) | CA9HIF1AHSD17B10MPOKDM4E | |
| SCHEMBL7006358 | 0.76 | HTR2A (0.43) | MEN1KMT2AALDH1A1LMNAHTR2A | |
| Bromide SCHEMBL15266090 | 0.76 | HMGCR (0.47) | MEN1KMT2ARECQLHPGDHSD17B10 | |
| SCHEMBL13885864 | 0.75 | ALOX5 (0.55) | MEN1KMT2ACYP3A4ALOX15ALOX5 | |
| SCHEMBL19542562 | 0.73 | PLA2G2A (0.46) | MEN1KMT2AHPGDHIF1AKDM4E | |
| SCHEMBL3631352 | 0.73 | GPR35 (0.50) | MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL13885884 | 0.73 | AKR1B1 (0.35) | HPGDHSD17B10ALOX15KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940769-B1 | DICARBOXYLIC ACID DERIVATIVES AND THEIR USE | BAYER IP GMBH (DE) | 2016-08-10 | — | — | EP | disclosed |
| EP-2142495-B1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | BAYER IP GMBH (DE) | 2016-04-27 | — | — | EP | disclosed |
| US-8217063-B2 | Lactam-substituted dicarboxylic acids and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-07-10 | — | — | US | disclosed |
| US-7985876-B2 | Substituted dibenzoic acid derivatives and use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-07-26 | — | — | US | disclosed |
| US-20100197680-A1 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-05 | — | — | US | disclosed |
| US-20100168240-A1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100029772-A1 | Dicarboxylic Acid Derivatives and their Use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | US | disclosed |
| EP-2142495-A1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-01-13 | — | — | EP | disclosed |
| EP-2142504-A2 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | Bayer Schering Pharma AG (DE) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008119457-A2 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119458-A1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-10-09 | — | — | WO | disclosed |
| EP-1940769-A1 | DICARBOXYLIC ACID DERIVATIVES AND THEIR USE | Bayer HealthCare AG (DE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007045433-A1 | DICARBOXYLIC ACID DERIVATIVES AND THEIR USE | BAYER HEALTHCARE AG (DE) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168240-A1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | BBOX1, DDC, DDT | MAOB 29/4885CA3 3118/4885CA6 671/4885 |
| US-20100197680-A1 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | DDO, DDC, BCAT2 | MAOB 2181/4885CA3 2149/4885CA6 793/4885 |
| US-20100029772-A1 | Dicarboxylic Acid Derivatives and their Use | PC, SLC25A1, GOT2 | MAOB 1969/4885CA3 1225/4885CA6 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.