Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.34 |
| ▸ | AKT2 | P31751 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532684 | 0.93 | ENPP2 (0.35) | ENPP2ALDH1A1GAACNR1BRD4 | |
| SCHEMBL8536225 | 0.82 | ADRA2C (0.40) | ALDH1A1GAACYP2C9S1PR1 | |
| SCHEMBL8535168 | 0.78 | PTGER4 (0.45) | ENPP2AKT2FFAR1FFAR4PTGER1 | |
| SCHEMBL8531524 | 0.74 | ENPP2 (0.39) | ENPP2CNR1BTKNR1H4 | |
| SCHEMBL8432423 | 0.72 | DHODH (0.40) | ALDH1A1GAACYP4F2CYP4A11MGLL | |
| SCHEMBL8429182 | 0.71 | PTGER4 (0.44) | ENPP2FFAR1FFAR4PTGER1PTGER4 | |
| SCHEMBL8535417 | 0.71 | PTGER4 (0.44) | ENPP2ALDH1A1FFAR1FFAR4PTGER1 | |
| SCHEMBL8431241 | 0.70 | PTGER4 (0.43) | ENPP2FFAR1FFAR4PTGER1PTGER4 | |
| SCHEMBL8432620 | 0.70 | F10 (0.38) | — | |
| SCHEMBL8430865 | 0.70 | PTGER4 (0.47) | ENPP2AKT2FFAR1FFAR4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |