Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27348223 | 0.85 | SLC9A1 (0.40) | PIN1PTGDR2RAB9AKMT2ASLC9A1 | |
| SCHEMBL8528490 | 0.83 | SLC9A1 (0.53) | SLC9A1 | |
| SCHEMBL27516092 | 0.81 | DCLRE1B (0.49) | DCLRE1BPTGER4PIN1PTGER2NOTUM | |
| SCHEMBL8610884 | 0.75 | ABL1 (0.44) | ACLYKMT2ALMNA | |
| SCHEMBL1495458 | 0.74 | LMNA (0.53) | ACLYNOTUMKMT2ALMNA | |
| SCHEMBL8528444 | 0.73 | SLC9A1 (0.50) | SLC9A1 | |
| SCHEMBL23908713 | 0.72 | DCLRE1B (0.51) | DCLRE1BACLYRAB9A | |
| SCHEMBL27456663 | 0.72 | DCLRE1B (0.48) | DCLRE1BPTGER4PIN1PTGER2NOTUM | |
| SCHEMBL10024224 | 0.71 | DCLRE1B (0.61) | DCLRE1BPTGER4PIN1PTGER2ACLY | |
| SCHEMBL269867 | 0.70 | HNF4A (0.53) | DCLRE1BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1055919-C | Arylbenzoylguanidin | MERCK PATENT GMBH (DE) | 2000-08-30 | — | — | CN | disclosed |
| EP-0699660-B1 | Arylbenzoylguanidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0699660-A2 | Arylbenzoylguanidines | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |
| CN-1117962-A | Arylbenzoylguanidin | MERCK PATENT GMBH (DE) | 1996-03-06 | — | — | CN | disclosed |