Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8534977

Cn1c(=S)sc2ccccc21.O=C(O)C(F)(F)F

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.47
RAB9A P51151 11/20 0.46
NPC1 O15118 10/20 0.46
SMN1; SMN2 Q16637 9/20 0.46
MAPT P10636 7/20 0.46
ALDH1A1 P00352 7/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C19 P33261 1/20 0.46
GAA P10253 1/20 0.45
MEN1 O00255 2/20 0.44
F12 P00748 1/20 0.44
KDM4E B2RXH2 3/20 0.42
NPSR1 Q6W5P4 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
NFKB1 P19838 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230331 0.83 F12 (0.59) KMT2ARAB9ANPC1SMN1; SMN2MAPT
SCHEMBL8699703 0.71 ALDH1A1 (0.55) SMN1; SMN2MAPTALDH1A1CYP3A4KDM4E
SCHEMBL19514739 0.70 ALDH1A1 (0.47) KMT2ARAB9ANPC1SMN1; SMN2MAPT
SCHEMBL19546037 0.69 POLB (0.48) KMT2ARAB9ANPC1SMN1; SMN2MAPT
Hydrochlorthiazide SCHEMBL9107872 0.69 F12 (0.42) KMT2ARAB9ANPC1SMN1; SMN2MAPT
SCHEMBL11082445 0.68 HTT (0.70) MAPTALDH1A1CYP1A2KDM4EL3MBTL1
SCHEMBL11082450 0.68 ALDH1A1 (0.42) KMT2ARAB9ANPC1SMN1; SMN2MAPT
SCHEMBL25002865 0.67 RAB9A (0.68) KMT2ARAB9ANPC1SMN1; SMN2MAPT
SCHEMBL5580041 0.67 ALDH1A1 (0.57) KMT2AMAPTALDH1A1CYP1A2MEN1
SCHEMBL13428993 0.67 RAB9A (0.76) KMT2ARAB9ANPC1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708796-B1 PROCESS FOR PREPARING COMPOSITES BASED ON ORIENTED MESOGENIC THERMOSET RESINS DOW CHEMICAL CO (US) 1998-05-27 EP disclosed
US-5637669-A THERMOSETTING RESIN; LIQUID CRYSTALLINE POLYMERS THE DOW CHEMICAL COMPANY (US) 1997-06-10 US disclosed
US-5621071-A Mesogenic novolacs and resins THE DOW CHEMICAL COMPANY (US) 1997-04-15 US disclosed
US-5486580-A Mesogenic novolacs and resins THE DOW CHEMICAL COMPANY (US) 1996-01-23 US disclosed
US-5424393-A Curing into liquid crystals THE DOW CHEMICAL COMPANY (US) 1995-06-13 US disclosed
WO-1995002631-A1 PROCESS FOR PREPARING COMPOSITES BASED ON ORIENTED MESOGENIC THERMOSET RESINS THE DOW CHEMICAL COMPANY (US) 1995-01-26 WO disclosed
US-5248360-A Saturating fiber substrates with curable thermosetting resin, arranging substrates into desired configuration, curing with application of heat and pressure THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5248740-A Thioepoxides, liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5182340-A Molding materials having shorter gel time with aliphatic amine curing agents THE DOW CHEMICAL COMPANY (US) 1993-01-26 US disclosed