Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787203 | 0.71 | CA1 (0.73) | CA1CA2SRCALDH1A1TLR2 | |
| SCHEMBL4203800 | 0.70 | ATM (0.55) | KCNN4ALDH1A1ATMMAPTHPGD | |
| SCHEMBL8529082 | 0.70 | KCNN4 (0.38) | KCNN4SRCALDH1A1ATMLMNA | |
| SCHEMBL4083040 | 0.69 | ATM (0.54) | KCNN4ALDH1A1ATMMAPTHPGD | |
| SCHEMBL4201299 | 0.69 | ALDH1A1 (0.52) | ALDH1A1ATMLMNAMAPTRAB9A | |
| SCHEMBL4205532 | 0.69 | ATM (0.45) | ALDH1A1ATMLMNAMAPTRAB9A | |
| O-Veratraldehyde SCHEMBL29923149 | 0.68 | SRC (0.67) | CA1CA2HSD17B10SRCTLR2 | |
| O-Veratraldehyde SCHEMBL28289918 | 0.68 | SRC (0.67) | CA1CA2HSD17B10SRCTLR2 | |
| O-Veratraldehyde SCHEMBL319070 | 0.68 | SRC (0.67) | CA1CA2HSD17B10SRCTLR2 | |
| SCHEMBL1597634 | 0.68 | CA1 (0.63) | CA1CA2SRCALDH1A1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843966-A | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |