Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25236329 | 0.82 | ALDH1A1 (0.38) | KDM4EALDH1A1HTR2BHTR6HSD17B10 | |
| SCHEMBL8538654 | 0.73 | PRMT5 (0.37) | PTGS1PTGS2KDM4EALDH1A1CA1 | |
| SCHEMBL8536634 | 0.73 | PARP1 (0.36) | PTGS1PTGS2ALDH1A1CA1CA2 | |
| SCHEMBL2914480 | 0.72 | MAPT (0.46) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL147219 | 0.69 | SLC9A1 (0.43) | KDM4EALDH1A1MAPTHSD17B10SLC9A1 | |
| SCHEMBL27965302 | 0.69 | SLC9A1 (0.43) | KDM4EHSD17B10SLC9A1KEAP1KDM5A | |
| SCHEMBL8535835 | 0.68 | HSD17B10 (0.39) | KDM4EMAPTCA1CA2CA9 | |
| SCHEMBL2723759 | 0.68 | LCK (0.41) | KDM4EHPGDKDM5AKDM4CKDM5B | |
| SCHEMBL2673505 | 0.67 | SLC9A1 (0.42) | KDM4EHSD17B10SLC9A1KEAP1KDM5A | |
| SCHEMBL13067164 | 0.67 | ESR2 (0.49) | KDM4EHSD17B10SLC9A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1048246-C | Indazolesulfonylurea derivative, use thereof, and intermediate for production thereof | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2000-01-12 | — | — | CN | disclosed |
| EP-0657450-B1 | INDAZOLESULFONYLUREA DERIVATIVE, USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1998-09-09 | — | — | EP | disclosed |
| US-5763616-A | HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| US-5670452-A | PREEMERGENCE HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5534481-A | Indazolesulfonylurea derivative, its use and intermediate for its production | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| CN-1110478-A | Indazolesulfonylurea derivative, use thereof, and intermediate for production thereof | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1995-10-18 | — | — | CN | disclosed |
| EP-0657450-A1 | INDAZOLESULFONYLUREA DERIVATIVE, USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | KumaiI Chemical Industry Co., Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |