Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539127 | 0.77 | CDK2 (0.35) | HSD17B10HTTCA12CA1CA2 | |
| SCHEMBL8538654 | 0.76 | PRMT5 (0.37) | LMNATSHRCA1CA2KDM4E | |
| SCHEMBL8536634 | 0.76 | PARP1 (0.36) | MAPK1CA1CA2GAA | |
| SCHEMBL27340761 | 0.70 | NCF1 (0.34) | LMNAHTTKDM4E | |
| SCHEMBL8539150 | 0.69 | ADRA2A (0.39) | HSD17B10LMNATSHRCA12CA1 | |
| SCHEMBL8535592 | 0.68 | PTGS1 (0.40) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL7545831 | 0.65 | ALOX15 (0.46) | HSD17B10NPSR1CA12CA1CA2 | |
| SCHEMBL201555 | 0.60 | S100A4 (0.38) | HSD17B10NPSR1MITFLMNATSHR | |
| SCHEMBL14059454 | 0.59 | NQO2 (0.49) | HSD17B10LMNACA12CA1CA2 | |
| SCHEMBL6114024 | 0.58 | HSD17B10 (0.66) | HSD17B10CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657450-B1 | INDAZOLESULFONYLUREA DERIVATIVE, USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1998-09-09 | — | — | EP | disclosed |
| US-5763616-A | HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| US-5670452-A | PREEMERGENCE HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5534481-A | Indazolesulfonylurea derivative, its use and intermediate for its production | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0657450-A1 | INDAZOLESULFONYLUREA DERIVATIVE, USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | KumaiI Chemical Industry Co., Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |