Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21026748 | 1.00 | TRPA1 (0.30) | TRPA1 | |
| SCHEMBL12446393 | 1.00 | TRPA1 (0.30) | TRPA1 | |
| SCHEMBL8536871 | 1.00 | TRPA1 (0.30) | TRPA1 | |
| SCHEMBL13475447 | 1.00 | TRPA1 (0.30) | TRPA1 | |
| SCHEMBL12520157 | 1.00 | TRPA1 (0.30) | TRPA1 | |
| SCHEMBL20169623 | 1.00 | TRPA1 (0.30) | TRPA1 | |
| SCHEMBL12441134 | 1.00 | TRPA1 (0.30) | TRPA1 | |
| SCHEMBL15905928 | 0.92 | DPP4 (0.31) | — | |
| SCHEMBL14015975 | 0.84 | — | — | |
| SCHEMBL20347789 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756799-A | HYDROGENATION CATALYSTS FOR OLEFINS USING RHODIUM CATALYST COMPLEXES | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 1998-05-26 | — | — | US | claimed |
| US-11124528-B2 | Process for preparing optically active 2,3-dihydrothiazolo[3,2-A]pyrimidin-4-ium compounds | BASF SE (DE) | 2021-09-21 | — | — | US | disclosed |
| US-11034703-B2 | Process for preparing chiral 2,3-dihydrothiazolo[3,2-A] pyrimidin-4-ium compounds | BASF SE (DE) | 2021-06-15 | — | — | US | disclosed |
| US-20210087207-A1 | PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS | BASF SE (DE) | 2021-03-25 | — | — | US | disclosed |
| US-20200055872-A1 | Process for Preparing Optically Active 2,3-Dihydrothiazolo[3,2-A]pyrimidin-4-ium Compounds | BASF SE (DE) | 2020-02-20 | — | — | US | disclosed |
| US-9802887-B2 | Process for the preparation of intermediates useful for the manufacture NEP inhibitors | NOVARTIS AG (CH) | 2017-10-31 | — | — | US | disclosed |
| EP-2609071-B1 | NEW PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE MANUFACTURE OF NEP INHIBITORS | NOVARTIS AG (CH) | 2016-09-21 | — | — | EP | disclosed |
| US-20150274650-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE MANUFACTURE NEP INHIBITORS | HOOK DAVID (CH) | 2015-10-01 | — | — | US | disclosed |
| US-9085529-B2 | Process for the preparation of intermediates useful for the manufacture NEP inhibitors | NOVARTIS AG (CH) | 2015-07-21 | — | — | US | disclosed |
| US-20130158275-A1 | NEW PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE MANUFACTURE NEP INHIBITORS | NOVARTIS AG (CH) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158275-A1 | NEW PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE MANUFACTURE NEP INHIBITORS | MME, DNPEP, REN | TRPA1 3939/4885 |
| US-20200055872-A1 | Process for Preparing Optically Active 2,3-Dihydrothiazolo[3,2-A]pyrimidin-4-ium Compounds | UMPS, UGP2, UGT1A4 | TRPA1 1508/4885 |
| US-11124528-B2 | Process for preparing optically active 2,3-dihydrothiazolo[3,2-A]pyrimidin-4-ium compounds | UMPS, UGP2, UGT1A4 | TRPA1 1508/4885 |
| US-20150274650-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE MANUFACTURE NEP INHIBITORS | MME, DNPEP, REN | TRPA1 4188/4885 |
| US-20210087207-A1 | PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS | UMPS, UGP2, XDH | TRPA1 2511/4885 |
| US-11034703-B2 | Process for preparing chiral 2,3-dihydrothiazolo[3,2-A] pyrimidin-4-ium compounds | UMPS, UGP2, XDH | TRPA1 2511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.