Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 9/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540845 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2AMMP13MMP14MEN1 | |
| SCHEMBL8542504 | 0.79 | HTT (0.42) | ALDH1A1HTTKMT2ASMN1; SMN2ACACB | |
| SCHEMBL3401516 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1POLBLIPE | |
| SCHEMBL8536210 | 0.76 | HTT (0.40) | ALDH1A1HTTKMT2ASMN1; SMN2ACACB | |
| SCHEMBL8579037 | 0.72 | HTT (0.41) | ALDH1A1HTTKMT2ASMN1; SMN2ACACB | |
| SCHEMBL8718627 | 0.70 | HTT (0.41) | ALDH1A1HTTKMT2ASMN1; SMN2ACACB | |
| SCHEMBL6647622 | 0.69 | ADRB1 (0.50) | ALDH1A1HTTKMT2ASMN1; SMN2ACACB | |
| SCHEMBL6647628 | 0.69 | ADRB1 (0.50) | ALDH1A1HTTKMT2ASMN1; SMN2ACACB | |
| SCHEMBL6174527 | 0.68 | HTT (0.46) | ALDH1A1HTTKMT2ASMN1; SMN2ACACB | |
| SCHEMBL7687627 | 0.68 | HTT (0.39) | ALDH1A1HTTKMT2ASMN1; SMN2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792780-A | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0657449-B1 | Azole compounds, their production and use as antifungal agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5545652-A | Triazole and imidazole compounds and their use as antifungal therapeutic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0657449-A1 | Azole compounds, their production and use as antifungal agents | Takeda Chemical Industries, Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |