Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 11/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542504 | 0.89 | HTT (0.42) | HTTKMT2ASMN1; SMN2ALDH1A1ACACB | |
| SCHEMBL8538552 | 0.82 | SCN5A (0.38) | ALDH1A1MMP13MMP14LIPE | |
| SCHEMBL8674229 | 0.77 | PDK2 (0.35) | ACACBLIPE | |
| SCHEMBL8535783 | 0.76 | ALDH1A1 (0.48) | HTTKMT2ASMN1; SMN2ALDH1A1ACACB | |
| SCHEMBL8579037 | 0.75 | HTT (0.41) | HTTKMT2ASMN1; SMN2ALDH1A1ACACB | |
| SCHEMBL8581320 | 0.75 | LIPE (0.46) | UGCGLIPE | |
| SCHEMBL6647628 | 0.74 | ADRB1 (0.50) | HTTKMT2ASMN1; SMN2ALDH1A1ACACB | |
| SCHEMBL6647622 | 0.74 | ADRB1 (0.50) | HTTKMT2ASMN1; SMN2ALDH1A1ACACB | |
| SCHEMBL8581221 | 0.73 | MMP13 (0.39) | MMP13MMP14LIPE | |
| SCHEMBL6647626 | 0.70 | HTT (0.39) | HTTKMT2ASMN1; SMN2ALDH1A1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792780-A | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0657449-B1 | Azole compounds, their production and use as antifungal agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5545652-A | Triazole and imidazole compounds and their use as antifungal therapeutic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0657449-A1 | Azole compounds, their production and use as antifungal agents | Takeda Chemical Industries, Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |