Sulfuric Acid

Sulfuric Acid

SCHEMBL3340873

COc1cc(N)ccc1N.O=S(=O)(O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2B known ✓ P18089 1/20 0.42
ALDH1A1 P00352 6/20 0.53
CYP3A4 P08684 3/20 0.53
TSHR P16473 3/20 0.53
HSD17B10 Q99714 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
THRB P10828 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
CASP1 P29466 1/20 0.53
RECQL P46063 1/20 0.53
HTT P42858 2/20 0.49
MAPT P10636 3/20 0.48
GAA P10253 2/20 0.48
MAPK1 P28482 1/20 0.48
PKM P14618 1/20 0.46
KDM4E B2RXH2 1/20 0.44
APP P05067 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL29558859 1.00 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRHSD17B10TDP1
Sulfuric Acid SCHEMBL8765503 0.98 ALDH1A1 (0.52) ALDH1A1CYP3A4TSHRHSD17B10TDP1
Methanesulfonamide SCHEMBL9482492 0.89 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRHSD17B10TDP1
SCHEMBL29375147 0.88 ALDH1A1 (0.67) ALDH1A1CYP3A4TSHRHSD17B10TDP1
SCHEMBL64099 0.88 ALDH1A1 (0.67) ALDH1A1CYP3A4TSHRHSD17B10TDP1
Hydrochloric Acid SCHEMBL10782973 0.86 ALDH1A1 (0.65) ALDH1A1CYP3A4TSHRHSD17B10TDP1
Hydrochloric Acid SCHEMBL10782376 0.86 ALDH1A1 (0.65) ALDH1A1CYP3A4TSHRHSD17B10TDP1
Sulfuric Acid SCHEMBL479725 0.85 CA1 (0.56) ALDH1A1CYP3A4TSHRHSD17B10TDP1
Sulfuric Acid SCHEMBL29558209 0.85 CA1 (0.56) ALDH1A1CYP3A4TSHRHSD17B10TDP1
Sulfuric Acid SCHEMBL7630472 0.85 ALDH1A1 (0.77) ALDH1A1CYP3A4TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114425027-A Hair dye and preparation method thereof 广州市芊彩化妆品有限公司 2022-05-03 CN claimed
US-4104021-A OXIDATION COLOR DYES COMBE INCORPORATED (US) 1978-08-01 US claimed
US-12583876-B2 Branched organosilicon compound, method of preparing same, and related compositions DOW SILICONES CORPORATION (US) 2026-03-24 US disclosed
EP-3493878-B1 COSMETIC COMPOSITION COMPRISING CURED SILICONE MATERIALS DOW SILICONES CORP (US) 2025-10-08 EP disclosed
US-12398270-B2 Acrylate-functional branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-08-26 US disclosed
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-07-29 US disclosed
US-12338259-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-06-24 US disclosed
US-12269833-B2 Branched organosilicon compound, method of preparing same, and compositions comprising same DOW SILICONES CORPORATION (US) 2025-04-08 US disclosed
US-12215198-B2 Branched organosilicon compound, method of preparing same, and compositions comprising same DOW SILICONES CORPORATION (US) 2025-02-04 US disclosed
US-20240245600-A1 ORRIS ROOT EXTRACTS, COMPOSITIONS, AND METHODS FOR SKIN APPLICATIONS ACCESS BUSINESS GROUP INT LLC (US) 2024-07-25 US disclosed
US-11986547-B2 Cosmetic composition comprising silicone materials DOW SILICONES CORPORATION (US) 2024-05-21 US disclosed
US-6387896-B1 GRAMNEGATIVE, GRAMPOSITVE BACTERIA PHARMACIA & UPJOHN CO. 2002-05-14 US disclosed
US-4994087-A Oxidation dyes producing red shades HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-02-19 US disclosed
EP-0319817-A2 Phenylamino- and phenylaminomethyl pyridines, and hair-dyeing products containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1989-06-14 EP disclosed
US-4756715-A Cosmetic carrier, surfactant, nitrodiphenylamine hair dyes HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-07-12 US disclosed
EP-0074243-B1 HAIR DYE COMPOSITION UNILEVER PLC (GB) 1986-11-26 EP disclosed
EP-0075242-B1 N-SUBSTITUTED 2,4-DIAMINO-M-XYLOLS AND HAIR COLOURING COMPOSITIONS CONTAINING THEM Henkel Kommanditgesellschaft auf Aktien (DE) 1985-03-13 EP disclosed
EP-0075242-A2 N-substituted 2,4-diamino-m-xylols and hair colouring compositions containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1983-03-30 EP disclosed
US-4229383-A FROM A CHLOROPHOSPHATE, AN ALKALI METAL OR AMMONIUM THIOCYANATE AND A PHENYLENEDIAMINE AMERICAN CYANAMID COMPANY (US) 1980-10-21 US disclosed
US-4104021-A OXIDATION COLOR DYES COMBE INCORPORATED (US) 1978-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215198-B2 Branched organosilicon compound, method of preparing same, and compositions comprising same ORC3, OXSR1, OR10J3 ADRA2B 1845/4885ALDH1A1 4242/4885CYP3A4 1394/4885
US-12583876-B2 Branched organosilicon compound, method of preparing same, and related compositions OXSR1, BRS3, NPSR1 ADRA2B 993/4885ALDH1A1 3531/4885CYP3A4 931/4885
US-12269833-B2 Branched organosilicon compound, method of preparing same, and compositions comprising same NR3C2, NR2E3, OXER1 ADRA2B 1113/4885ALDH1A1 4302/4885CYP3A4 1926/4885
US-12338259-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, ORC3 ADRA2B 2224/4885ALDH1A1 3760/4885CYP3A4 1716/4885
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, OXER1 ADRA2B 511/4885ALDH1A1 2965/4885CYP3A4 1178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.