Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.35 |
| ▸ | CA2 | P00918 | 12/20 | 0.35 |
| ▸ | CA9 | Q16790 | 9/20 | 0.35 |
| ▸ | CA12 | O43570 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532203 | 0.75 | CA1 (0.36) | CA1CA2CA9CA12MAPT | |
| SCHEMBL8531517 | 0.71 | ITGB3 (0.35) | CA1CA2CA9CA12MAPT | |
| SCHEMBL8536201 | 0.70 | ITGB3 (0.35) | CA1CA2CA9CA12MAPT | |
| Propionic Acid SCHEMBL8534857 | 0.66 | USP28 (0.40) | CA1CA2CA9CA12MAPT | |
| SCHEMBL8499992 | 0.65 | MEN1 (0.42) | CA1CA2MAPTF2 | |
| SCHEMBL8697020 | 0.64 | CA1 (0.37) | CA1CA2CA9CA12MAPT | |
| SCHEMBL1593097 | 0.63 | CA1 (0.64) | CA1CA2CA9CA12MAPT | |
| SCHEMBL8372024 | 0.62 | POLB (0.54) | F2TMPRSS6 | |
| SCHEMBL7372864 | 0.62 | KMT2A (0.57) | CA1CA2CA9CA12MAPT | |
| SCHEMBL2833035 | 0.62 | ITGB3 (0.48) | CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |