Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536201 | 0.75 | ITGB3 (0.35) | MAPTSMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL8532203 | 0.73 | CA1 (0.36) | MAPTALDH1A1CA1CA2CA12 | |
| SCHEMBL8531517 | 0.73 | ITGB3 (0.35) | MAPTSMN1; SMN2ALDH1A1CA1CA2 | |
| Propionic Acid SCHEMBL8534858 | 0.69 | RORC (0.36) | MAPTSMN1; SMN2ALDH1A1CRHBPCRHR2 | |
| Propionic Acid SCHEMBL8698740 | 0.66 | HDAC1 (0.33) | LMNA | |
| SCHEMBL8534236 | 0.66 | CA1 (0.40) | MAPTSMN1; SMN2CA1CA2CA12 | |
| SCHEMBL8428884 | 0.66 | ITGB3 (0.42) | MAPTSMN1; SMN2CA1CA2CA12 | |
| SCHEMBL8536127 | 0.66 | CA1 (0.35) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL8532987 | 0.65 | ITGB3 (0.38) | MAPTSMN1; SMN2CA1CA2CA12 | |
| SCHEMBL1592707 | 0.64 | LMNA (0.53) | MAPTSMN1; SMN2ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |