Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 8/20 | 0.35 |
| ▸ | CA2 | P00918 | 8/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531517 | 0.89 | ITGB3 (0.35) | ITGB3ITGA2BCA1CA2CA9 | |
| SCHEMBL8532203 | 0.84 | CA1 (0.36) | ITGB3ITGA2BCA1CA2CA9 | |
| Propionic Acid SCHEMBL8534857 | 0.75 | USP28 (0.40) | CA1CA2CA9CA12MAPT | |
| SCHEMBL8428884 | 0.74 | ITGB3 (0.42) | ITGB3ITGA2BCA1CA2CA9 | |
| SCHEMBL8501204 | 0.70 | PTGER1 (0.42) | ITGB3ITGA2BCA1CA2CA9 | |
| SCHEMBL7376447 | 0.70 | MAPT (0.47) | ITGB3ITGA2BMAPTLMNAKMT2A | |
| SCHEMBL8532458 | 0.70 | ITGB3 (0.40) | ITGB3ITGA2BMAPT | |
| SCHEMBL8501517 | 0.70 | PFKFB3 (0.46) | MAPTLMNAKMT2AMEN1HPGD | |
| SCHEMBL8536127 | 0.70 | CA1 (0.35) | CA1CA2CA9CA12MAPT | |
| SCHEMBL8500575 | 0.69 | MEN1 (0.42) | CA1CA2FFAR1FFAR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |