Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871442 | 0.89 | ADAM17 (0.46) | OPRM1OPRL1EPHX2ADAM17KDM4E | |
| SCHEMBL8053435 | 0.87 | ADAM17 (0.45) | OPRM1OPRL1EPHX2ADAM17KDM4E | |
| Hydrochloric Acid SCHEMBL8049068 | 0.86 | ADAM17 (0.44) | OPRM1OPRL1EPHX2ADAM17LMNA | |
| SCHEMBL8049066 | 0.85 | EPHX2 (0.44) | OPRM1OPRL1EPHX2ADAM17LMNA | |
| SCHEMBL8050802 | 0.85 | ADAM17 (0.43) | OPRM1OPRL1DPP4EPHX2ADAM17 | |
| SCHEMBL27377447 | 0.83 | OPRM1 (0.51) | OPRM1OPRL1DPP4EPHX2ADAM17 | |
| SCHEMBL27377484 | 0.83 | OPRM1 (0.51) | OPRM1OPRL1DPP4EPHX2ADAM17 | |
| SCHEMBL8586277 | 0.81 | DPP4 (0.51) | OPRM1OPRL1DPP4EPHX2ADAM17 | |
| SCHEMBL15927866 | 0.80 | ADAM17 (0.46) | OPRM1OPRL1EPHX2ADAM17KDM4E | |
| SCHEMBL14661822 | 0.79 | OPRM1 (0.47) | OPRM1OPRL1DPP4EPHX2ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817776-A | TECHNETIUM 99 COMPLEXES, SINGLE PHOTON EMISSION TOMOGRAPHY | EMORY UNIVERSITY (US) | 1998-10-06 | — | — | US | disclosed |
| US-5808146-A | Amino acid analogs for tumor imaging | EMORY UNIVERSITY (US) | 1998-09-15 | — | — | US | disclosed |
| WO-1997017092-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1997-05-15 | — | — | WO | disclosed |