Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377447 | 1.00 | OPRM1 (0.51) | OPRM1OPRL1DPP4EPHX2SIGMAR1 | |
| SCHEMBL31471360 | 0.83 | OPRM1 (0.55) | OPRM1OPRL1DPP4EPHX2SIGMAR1 | |
| SCHEMBL8536152 | 0.83 | OPRM1 (0.47) | OPRM1OPRL1DPP4EPHX2SIGMAR1 | |
| SCHEMBL14661822 | 0.83 | OPRM1 (0.47) | OPRM1OPRL1DPP4EPHX2SIGMAR1 | |
| SCHEMBL5039 | 0.81 | ALDH1A1 (0.51) | OPRM1OPRL1DPP4KDM4ELMNA | |
| SCHEMBL1589872 | 0.81 | ALDH1A1 (0.51) | OPRM1OPRL1DPP4KDM4ELMNA | |
| SCHEMBL871442 | 0.80 | ADAM17 (0.46) | OPRM1OPRL1EPHX2KDM4ELMNA | |
| SCHEMBL15927866 | 0.78 | ADAM17 (0.46) | OPRM1OPRL1EPHX2KDM4ELMNA | |
| SCHEMBL17103459 | 0.78 | PKM (0.55) | KDM4EPOLBPKMMAPTMEN1 | |
| SCHEMBL28404362 | 0.78 | DDB1 (0.50) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050016-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2024-03-07 | — | — | WO | disclosed |