Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936878 | 0.88 | DPP4 (0.46) | DPP4OPRM1OPRL1EPHX2CYP2C19 | |
| SCHEMBL8536152 | 0.81 | OPRM1 (0.47) | DPP4OPRM1OPRL1EPHX2SIGMAR1 | |
| SCHEMBL8050802 | 0.79 | ADAM17 (0.43) | DPP4OPRM1OPRL1EPHX2SMN1; SMN2 | |
| SCHEMBL2640274 | 0.79 | EPHX2 (0.47) | DPP4OPRM1OPRL1EPHX2AGTR2 | |
| SCHEMBL7938718 | 0.78 | CTSL (0.41) | EPHX2CYP2C19SMN1; SMN2AGTR2TSHR | |
| SCHEMBL31471412 | 0.78 | DPP4 (0.44) | DPP4OPRM1OPRL1EPHX2CYP2C19 | |
| SCHEMBL23364774 | 0.77 | DPP4 (0.61) | DPP4OPRM1OPRL1EPHX2SIGMAR1 | |
| SCHEMBL7926366 | 0.77 | DPP4 (0.57) | DPP4OPRM1OPRL1EPHX2SIGMAR1 | |
| SCHEMBL11945826 | 0.75 | OPRM1 (0.55) | DPP4OPRM1OPRL1EPHX2SIGMAR1 | |
| SCHEMBL31471360 | 0.75 | OPRM1 (0.55) | DPP4OPRM1OPRL1EPHX2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817776-A | TECHNETIUM 99 COMPLEXES, SINGLE PHOTON EMISSION TOMOGRAPHY | EMORY UNIVERSITY (US) | 1998-10-06 | — | — | US | disclosed |
| US-5808146-A | Amino acid analogs for tumor imaging | EMORY UNIVERSITY (US) | 1998-09-15 | — | — | US | disclosed |
| WO-1997017092-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1997-05-15 | — | — | WO | disclosed |