Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 9/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536393 | 0.94 | CTSD (0.52) | CTSDCA2MMP2REN | |
| SCHEMBL7345648 | 0.84 | CA2 (0.54) | CTSDCA2 | |
| Hydrochloric Acid SCHEMBL8535408 | 0.84 | MMP2 (0.53) | CTSDCA2MMP2 | |
| SCHEMBL7268478 | 0.83 | CTSD (0.54) | CTSD | |
| SCHEMBL623353 | 0.83 | CTSD (0.52) | CTSD | |
| SCHEMBL623404 | 0.83 | CTSD (0.52) | CTSD | |
| SCHEMBL7332623 | 0.82 | CA2 (0.57) | CTSDCA2 | |
| SCHEMBL7275501 | 0.81 | MMP2 (0.50) | MMP2 | |
| SCHEMBL621676 | 0.80 | CTSD (0.50) | CTSDREN | |
| SCHEMBL7333197 | 0.80 | CA2 (0.54) | CTSDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712417-A | Inhibitors of retroviral proteases | ABBOTT LABORATORIES (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0428849-A2 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | disclosed |