Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149445 | 0.89 | TERT (0.36) | KDM4ESMN1; SMN2 | |
| SCHEMBL8910714 | 0.88 | ALDH1A1 (0.34) | KDM4EALDH1A1LMNAHSP90AA1MAPT | |
| SCHEMBL8909578 | 0.86 | HPGD (0.41) | RAB9AKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8146941 | 0.86 | GRIN1 (0.39) | KDM4ESMN1; SMN2 | |
| SCHEMBL8154329 | 0.85 | KMT2A (0.31) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8910392 | 0.85 | CCNB2 (0.32) | LMNAMAPTHTT | |
| SCHEMBL8142537 | 0.85 | MYC (0.34) | RAB9AKDM4EALDH1A1MAPTHTT | |
| SCHEMBL8142555 | 0.85 | NPC1 (0.40) | RAB9A | |
| SCHEMBL9057850 | 0.82 | MYC (0.36) | — | |
| SCHEMBL9048962 | 0.82 | PDCD1 (0.34) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770598-A | ANTITUMOR AGENTS; REACTING WITH CARBONYL DIIMIDAZOLE AND AMIDOXIMES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1998-06-23 | — | — | US | disclosed |