Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | METAP1 | P53582 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532071 | 0.93 | ACHE (0.52) | HTR2CALDH1A1GAAHPGDKMT2A | |
| SCHEMBL8534917 | 0.92 | ACHE (0.51) | HTR2CALDH1A1GAAHPGDKMT2A | |
| SCHEMBL8536631 | 0.91 | HTR2C (0.52) | HTR2CALDH1A1GAAHPGDKMT2A | |
| SCHEMBL9344339 | 0.81 | LMNA (0.54) | HTR2CALDH1A1HPGDCYP19A1ACHE | |
| SCHEMBL9344141 | 0.81 | HTR2C (0.49) | HTR2CALDH1A1HPGDCYP19A1ACHE | |
| SCHEMBL8531749 | 0.81 | CYP19A1 (0.52) | HTR2CALDH1A1KMT2ACYP19A1ACHE | |
| SCHEMBL7672871 | 0.80 | CYP19A1 (0.57) | HTR2CALDH1A1CYP19A1ACHEHTR1A | |
| SCHEMBL30423421 | 0.76 | METAP1 (0.74) | HTR2CACHEHTR1ASIGMAR1METAP1 | |
| SCHEMBL6689014 | 0.75 | CYP19A1 (0.61) | HTR2CALDH1A1CYP19A1ACHEHTR1A | |
| Hydrochloric Acid SCHEMBL29583950 | 0.75 | METAP1 (0.74) | HTR2CACHEHTR1ASIGMAR1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |