Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536631 | 0.90 | HTR2C (0.52) | HTR2CACHECYP19A1ALDH1A1HPGD | |
| SCHEMBL8532071 | 0.88 | ACHE (0.52) | SMN1; SMN2HTR2CACHECYP19A1ALDH1A1 | |
| SCHEMBL9344141 | 0.86 | HTR2C (0.49) | LMNASMN1; SMN2HTR2CACHECYP19A1 | |
| SCHEMBL8534917 | 0.85 | ACHE (0.51) | SMN1; SMN2HTR2CACHECYP19A1ALDH1A1 | |
| SCHEMBL8536658 | 0.81 | HTR2C (0.50) | HTR2CACHECYP19A1ALDH1A1HPGD | |
| SCHEMBL8536795 | 0.79 | CYP19A1 (0.54) | SMN1; SMN2HTR2CACHECYP19A1ALDH1A1 | |
| SCHEMBL7167409 | 0.75 | CYP19A1 (0.53) | SMN1; SMN2HTR2CACHECYP19A1ALDH1A1 | |
| SCHEMBL27646285 | 0.75 | SIGMAR1 (0.68) | HTR2CACHECYP19A1HTR1ASIGMAR1 | |
| SCHEMBL27582477 | 0.74 | CYP19A1 (0.52) | SMN1; SMN2HTR2CACHECYP19A1ALDH1A1 | |
| SCHEMBL7672871 | 0.73 | CYP19A1 (0.57) | SMN1; SMN2HTR2CACHECYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292768-A | Compound effective as cerebral insufficiency improver | SUNTORY LIMITED (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |