Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.56 |
| ▸ | NQO2 | P16083 | 5/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.51 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759942 | 0.76 | GSTP1 (0.53) | MTNR1AMTNR1BNQO2GSTP1GSTM2 | |
| SCHEMBL8534889 | 0.75 | MTNR1A (0.60) | MTNR1AMTNR1BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8447846 | 0.74 | GSTP1 (0.57) | MTNR1AMTNR1BGSTP1GSTM2MAPT | |
| Hydrochloric Acid SCHEMBL9009890 | 0.74 | MTNR1A (0.59) | MTNR1AMTNR1BSMN1; SMN2NPC1RAB9A | |
| Water SCHEMBL8536059 | 0.74 | MTNR1A (0.59) | MTNR1AMTNR1BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1880932 | 0.73 | NPC1 (0.62) | MTNR1AMTNR1BNQO2MAPTSMN1; SMN2 | |
| SCHEMBL8535790 | 0.73 | ALDH1A1 (0.46) | MAPTCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL11208688 | 0.71 | APEX1 (0.56) | MAPTSMN1; SMN2NPC1CYP3A4RAB9A | |
| SCHEMBL2062588 | 0.70 | NQO2 (0.51) | MTNR1AMTNR1BNQO2MEN1KMT2A | |
| SCHEMBL6370055 | 0.70 | ALDH1A1 (0.57) | MAPTSMN1; SMN2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591059-B1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | OREAL (FR) | 1998-04-15 | — | — | EP | disclosed |
| US-5534036-A | Keratinous fiber dyeing methods and compositions which contain sulfated methaphenylenediamine couplers in combination with oxidation dye precursors | L'OREAL (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0591059-A1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | L'OREAL (FR) | 1994-04-06 | — | — | EP | disclosed |