SCHEMBL459542

SCHEMBL459542

CCc1ccc(N)c(CC)c1N

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.38
HTT P42858 1/20 0.38
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
GABRA1 P14867 2/20 0.31
GABRB2 P47870 2/20 0.31
CTRC Q99895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29430589 1.00 POLB (0.38) POLBHTTALDH1A1MAPTNOS3
SCHEMBL393531 0.85 POLB (0.35) POLBHTTALDH1A1MAPTNOS3
SCHEMBL8535795 0.85 NOS3 (0.34) POLBHTTALDH1A1MAPTNOS3
SCHEMBL396164 0.83 POLB (0.41) POLBHTTALDH1A1MAPTNOS3
SCHEMBL29199935 0.83 POLB (0.33) POLBHTTALDH1A1MAPT
SCHEMBL7060663 0.82 NOS3 (0.37) POLBHTTALDH1A1MAPTNOS3
Hydrochloric Acid SCHEMBL5510042 0.81 POLB (0.40) POLBHTTALDH1A1MAPTNOS3
Bromide SCHEMBL16928609 0.81 POLB (0.40) POLBHTTALDH1A1MAPTNOS3
Water SCHEMBL188047 0.81 POLB (0.44) POLBHTTALDH1A1MAPTNOS3
Hydrochloric Acid SCHEMBL233673 0.81 POLB (0.40) POLBHTTALDH1A1MAPTNOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12077644-B2 Amide acid oligomer process for molding polyimide composites KANEKA AMERICAS HOLDING, INC. (US) 2024-09-03 US claimed
CN-112888726-B Novel amic acid oligomer process for molding polyimide composites 钟化美洲控股公司 2023-10-03 CN claimed
US-20210340344-A1 Novel Amide Acid Oligomer Process For Molding Polyimide Composites KANEKA AMERICAS HOLDING, INC. (US) 2021-11-04 US claimed
CN-112888726-A Novel amic acid oligomer process for molding polyimide composites 钟化美洲控股公司 2021-06-01 CN claimed
US-10815390-B2 Polyimide resin composition and varnish produced from terminal-modified imide oligomer prepared using 2-phenyl-4,4′-diaminodiphenyl ether and thermoplastic aromatic polyimide prepared using oxydiphthalic acid, polyimide resin composition molded article and prepreg having excellent heat resistance and mechanical characteristic, and fiber-reinforced composite material thereof KANEKA CORPORATION (JP) 2020-10-27 US claimed
US-20180273798-A1 POLYIMIDE RESIN COMPOSITION AND VARNISH PRODUCED FROM TERMINAL-MODIFIED IMIDE OLIGOMER PREPARED USING 2-PHENYL-4,4'-DIAMINODIPHENYL ETHER AND THERMOPLASTIC AROMATIC POLYIMIDE PREPARED USING OXYDIPHTHALIC ACID, POLYIMIDE RESIN COMPOSITION MOLDED ARTICLE AND PREPREG HAVING EXCELLENT HEAT RESISTANCE AND MECHANICAL CHARACTERISTIC, AND FIBER-REINFORCED COMPOSITE MATERIAL THEREOF KANEKA CORPORATION (JP) 2018-09-27 US claimed
US-10017666-B2 Polyimide resin composition and varnish produced from terminal-modified imide oligomer prepared using 2-phenyl-4,4′-diaminodiphenyl ether and thermoplastic aromatic polyimide prepared using oxydiphthalic acid, polyimide resin composition molded article and prepreg having excellent heat resistance and mechanical characteristic, and fiber-reinforced composite material thereof KANEKA CORPORATION (JP) 2018-07-10 US claimed
CN-103547568-B Terminally modified imide oligomer using 2-phenyl-4, 4' -diaminodiphenyl ether, mixture thereof, varnish, and cured resin KANEKA CORP. (JP) 2016-04-13 CN claimed
CN-101440207-A Integral skin molded article, method of preparing an integral skin molded article and laminate having integral skin made of polyurethane using the reaction injection molding process SUMIKA BAYER URETHANE CO LTD (JP) 2009-05-27 CN claimed
EP-0494546-B1 Foamed polyurea elastomer HUNTSMAN CORP (US) 1996-07-10 EP claimed
EP-0442084-B1 Two-component polyurethane adhesive MILES INC (US) 1994-02-16 EP claimed
US-5059672-A Polyurea coatings; high tensile strength, chemical and corrosion resistant THARE COAT, INC. (US) 1991-10-22 US claimed
US-4820743-A BLEND OF POLYETHERPOLYOL AND POLYAMINE, AND UNSATURATED MONOMER SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-11 US claimed
US-12590184-B2 Polyimide resin molded body and production method for same TOYO SEIKAN GROUP HOLDINGS, LTD. (JP) 2026-03-31 US disclosed
US-12570864-B2 Storage-stable pigmented formulations containing isocyanate groups and use thereof COVESTRO DEUTSCHLAND AG (DE) 2026-03-10 US disclosed
US-12410276-B2 Method of recycling polyurethane materials CARPENTER ENGINEERED FOAMS BELGIUM BV (BE) 2025-09-09 US disclosed
EP-0004640-A2 Process for producing elastomeric mouldings Mobay Chemical Corporation (US) 1979-10-17 EP disclosed
US-3977987-A Fuel and lubricant compositions containing novel pyrrolidinyl or piperidinyl-substituted diphenyl alkane antioxidants UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-08-31 US disclosed
US-3968079-A Rubber compositions stabilized with heterocyclic nitrogenous antioxidants UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-07-06 US disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570864-B2 Storage-stable pigmented formulations containing isocyanate groups and use thereof RB1, ALDH1A2, IDH3A POLB 3564/4885HTT 216/4885ALDH1A1 433/4885
US-12590184-B2 Polyimide resin molded body and production method for same PBRM1, FGB, PF4 POLB 1000/4885HTT 2073/4885ALDH1A1 3284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.