Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544166 | 0.82 | CNR1 (0.35) | PARP1PARP10PARP14BTKF2 | |
| SCHEMBL8539472 | 0.74 | PARP1 (0.47) | PARP1PARP10PARP14PARP15SIRT2 | |
| SCHEMBL8536836 | 0.72 | MGLL (0.33) | MAPTBTKF2F10 | |
| SCHEMBL8538344 | 0.72 | BTK (0.36) | PARP1PARP10PARP14PARP15SIRT1 | |
| SCHEMBL8530521 | 0.71 | ENPP2 (0.47) | MEN1KMT2A | |
| SCHEMBL8432812 | 0.70 | ITGB3 (0.39) | MEN1KMT2APOLBKDM4E | |
| SCHEMBL8432519 | 0.69 | PTGER4 (0.45) | MEN1KMT2A | |
| SCHEMBL8432447 | 0.69 | PARP1 (0.37) | PARP1PARP10ALDH1A1MAPTHPGD | |
| SCHEMBL8431178 | 0.68 | PLA2G10 (0.39) | MAPTMEN1KMT2ACYP2C19 | |
| SCHEMBL8429316 | 0.67 | ITGB3 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |