Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536796 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KCNK3KCNK9PLAUMEN1 | |
| SCHEMBL8536831 | 0.80 | KCNK3 (0.46) | SIRT2ALDH1A1KCNK3KCNK9PLAU | |
| SCHEMBL7497379 | 0.79 | PARP1 (0.51) | PARP1PARP15PARP14PARP10ALDH1A1 | |
| SCHEMBL7497389 | 0.79 | PARP1 (0.51) | PARP1PARP15PARP14PARP10ALDH1A1 | |
| SCHEMBL7509243 | 0.76 | ITGB3 (0.55) | PARP1PARP15PARP14PARP10ALDH1A1 | |
| SCHEMBL7509239 | 0.76 | ITGB3 (0.55) | PARP1PARP15PARP14PARP10ALDH1A1 | |
| SCHEMBL8542403 | 0.75 | KCNK3 (0.41) | SIRT2ALDH1A1KCNK3KCNK9MEN1 | |
| SCHEMBL8537945 | 0.75 | PTGS1 (0.46) | SIRT2KCNK3KCNK9MEN1KMT2A | |
| SCHEMBL8536790 | 0.74 | PARP1 (0.41) | PARP1PARP15PARP14PARP10SIRT2 | |
| SCHEMBL8540350 | 0.73 | ITGB3 (0.50) | PARP1PARP15PARP14PARP10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |