Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745549 | 0.83 | ADRA2A (0.32) | — | |
| SCHEMBL957226 | 0.76 | FFAR3 (0.35) | — | |
| SCHEMBL215964 | 0.76 | FFAR3 (0.35) | — | |
| SCHEMBL3785080 | 0.72 | FDPS (0.37) | — | |
| SCHEMBL19886164 | 0.72 | FDPS (0.37) | — | |
| SCHEMBL155767 | 0.72 | FDPS (0.37) | — | |
| Acetamide SCHEMBL5961960 | 0.72 | LMNA (0.31) | — | |
| SCHEMBL28621283 | 0.70 | GSR (0.43) | — | |
| Glycine SCHEMBL7512436 | 0.70 | GLRA1 (0.62) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL29016771 | 0.68 | HTR2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3033409-B1 | COMPOSITION | CATEXEL TECH LIMITED (GB) | 2021-09-22 | — | — | EP | disclosed |
| EP-3033409-A1 | COMPOSITION | Chemsenti Limited (GB) | 2016-06-22 | — | — | EP | disclosed |
| WO-2015022502-A1 | COMPOSITION | CHEMSENTI LIMITED (GB) | 2015-02-19 | — | — | WO | disclosed |
| EP-0638353-B1 | Membranes for the separation of carbon dioxide gas | SUMITOMO ELECTRIC INDUSTRIES (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5445669-A | Hydrogel film of a cross-linked, vinyl alcohol-acrylic acid copolymer impregnated with an aqueous solution containing a carbon dioxide carrier | SUMITOMO ELECTRIC INDUSTRIES, LTD. | 1995-08-29 | — | — | US | disclosed |
| EP-0638353-A1 | Membrane for the separation of carbon dioxide | Sumitomo Electric Industries, Ltd. (JP) | 1995-02-15 | — | — | EP | disclosed |