Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537425 | 0.78 | MEN1 (0.34) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6958143 | 0.74 | HTR2B (0.49) | TSHRMAPTCA12CA1CA2 | |
| SCHEMBL8537419 | 0.73 | RAPGEF4 (0.34) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL1301606 | 0.72 | CYP19A1 (0.71) | ALDH1A1HPGDKDM4EHSD17B10CYP19A1 | |
| SCHEMBL27820726 | 0.72 | CYP19A1 (0.71) | ALDH1A1HPGDKDM4EHSD17B10CYP19A1 | |
| SCHEMBL8538683 | 0.71 | KMT2A (0.39) | HPGDKDM4EHSD17B10CYP19A1NPC1 | |
| SCHEMBL5049441 | 0.70 | CYP19A1 (0.71) | ALDH1A1HPGDKDM4EHSD17B10CYP19A1 | |
| SCHEMBL6954315 | 0.69 | DAO (0.34) | TSHRSMN1; SMN2MAPTGAA | |
| SCHEMBL11788874 | 0.69 | DAO (0.43) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL6954786 | 0.68 | SMN1; SMN2 (0.50) | ALDH1A1HPGDKDM4EHSD17B10CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |