Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537422 | 0.78 | ALDH1A1 (0.41) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL8336068 | 0.77 | PPARG (0.31) | DAOPPARGPPARA | |
| SCHEMBL8537419 | 0.73 | RAPGEF4 (0.34) | KMT2ANPC1RAB9ACA12CA1 | |
| SCHEMBL8538467 | 0.71 | PPARG (0.37) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL8343243 | 0.69 | ADORA3 (0.34) | NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6954315 | 0.69 | DAO (0.34) | DAOSMN1; SMN2PPARG | |
| SCHEMBL11788874 | 0.69 | DAO (0.43) | MEN1KMT2ADAOSMN1; SMN2 | |
| SCHEMBL8336040 | 0.68 | KDM6B (0.30) | KDM6BKDM4AKDM4DHIF1ANKDM5B | |
| SCHEMBL6954786 | 0.68 | SMN1; SMN2 (0.50) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL6958143 | 0.67 | HTR2B (0.49) | CA12CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |