Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538591 | 0.82 | CYP19A1 (0.38) | KMT2AHPGDCYP19A1PTPN1L3MBTL1 | |
| SCHEMBL7375775 | 0.81 | HTR2B (0.50) | PTGS2DAOGPR84HTR2BHTR3A | |
| SCHEMBL8538469 | 0.78 | ALOX5 (0.38) | KMT2AHPGDPTGS2PTPN1KDM4E | |
| SCHEMBL8534402 | 0.77 | CYP19A1 (0.36) | KMT2AHPGDCYP19A1PTGS2PTPN1 | |
| SCHEMBL8538467 | 0.75 | PPARG (0.37) | KMT2AHPGDPTGS2PTPN1L3MBTL1 | |
| SCHEMBL8586973 | 0.74 | POLB (0.44) | KMT2AHPGDL3MBTL1KDM4ECA12 | |
| SCHEMBL11787842 | 0.74 | ALDH1A1 (0.45) | KMT2AHPGDPTGS2KDM4EDAO | |
| SCHEMBL6957097 | 0.74 | CYSLTR1 (0.41) | PTPN1L3MBTL1GPR84 | |
| SCHEMBL6958143 | 0.73 | HTR2B (0.49) | PTPN1DAOHTR2BHTR3ACA12 | |
| SCHEMBL6959585 | 0.71 | FABP4 (0.45) | KMT2AHPGDL3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |