Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 3/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537425 | 0.73 | MEN1 (0.34) | DAOCTSBPPARGCA12CA1 | |
| SCHEMBL8537422 | 0.73 | ALDH1A1 (0.41) | CA12CA1CA2CA4CA6 | |
| SCHEMBL11788874 | 0.69 | DAO (0.43) | DAOMAPTALDH1A1KMT2APKM | |
| SCHEMBL6954786 | 0.68 | SMN1; SMN2 (0.50) | DAOPPARGCA12CA1CA2 | |
| SCHEMBL6954315 | 0.67 | DAO (0.34) | DAOPPARGMAPTPKMTSHR | |
| SCHEMBL6958143 | 0.67 | HTR2B (0.49) | DAOPPARGCA12CA1CA2 | |
| SCHEMBL6956094 | 0.66 | AKR1C3 (0.46) | DAOMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL6961428 | 0.66 | MEN1 (0.45) | DAOCA12CA9MAPTALDH1A1 | |
| SCHEMBL8538469 | 0.65 | ALOX5 (0.38) | KDM4EHPGDKMT2ANPC1RAB9A | |
| SCHEMBL6954509 | 0.65 | NPC1 (0.47) | DAOCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |