Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608505 | 0.81 | KMT2A (0.44) | VCAM1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL12039494 | 0.76 | CASP3 (0.44) | KDM4ELMNAMAPTL3MBTL1NPSR1 | |
| SCHEMBL11731415 | 0.74 | LMNA (0.42) | KDM4ELMNAMAPTL3MBTL1NPC1 | |
| SCHEMBL27214761 | 0.73 | KCNJ1 (0.55) | FBP1VCAM1LMNAMAPTNPC1 | |
| SCHEMBL8538325 | 0.73 | KCNJ1 (0.41) | KDM4ELMNAMAPTALDH1A1TDP1 | |
| SCHEMBL8815587 | 0.73 | MMP2 (0.31) | — | |
| SCHEMBL1811649 | 0.71 | LMNA (0.46) | KDM4ELMNAMAPTL3MBTL1NPC1 | |
| SCHEMBL8538501 | 0.70 | LMNA (0.44) | KDM4ELMNAMAPTL3MBTL1NPC1 | |
| SCHEMBL11848697 | 0.70 | LMNA (0.44) | KDM4ELMNAMAPTL3MBTL1NPC1 | |
| SCHEMBL6428842 | 0.68 | KMT2A (0.64) | KDM4ELMNAMAPTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726195-A | Aminoacyl adenylate mimics as novel antimicrobial and antiparasitic agents | CUBIST PHARMACEUTICALS, INC. (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1997005132-A1 | AMINOACYL ADENYLATE MIMICS AS NOVEL ANTIMICROBIAL AND ANTIPARASITIC AGENTS | CUBIST PHARMACEUTICALS, INC. (US) | 1997-02-13 | — | — | WO | disclosed |