Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538200 | 0.73 | KCNJ1 (0.41) | KCNJ1KCNH2MAPTNOTUMF2 | |
| SCHEMBL8537838 | 0.73 | FBP1 (0.39) | KCNJ1KCNH2MAPTALDH1A1LMNA | |
| SCHEMBL1269000 | 0.71 | KCNJ1 (0.68) | KCNJ1KCNH2MAPTNOTUMF2 | |
| SCHEMBL8815587 | 0.68 | MMP2 (0.31) | — | |
| SCHEMBL12615985 | 0.66 | NOTUM (0.78) | KCNJ1MAPTNOTUMF2ALDH1A1 | |
| SCHEMBL12039494 | 0.66 | CASP3 (0.44) | MAPTALDH1A1LMNACA12CA9 | |
| SCHEMBL11731415 | 0.64 | LMNA (0.42) | MAPTALDH1A1LMNAPOLBTDP1 | |
| SCHEMBL5148009 | 0.62 | LMNA (0.51) | KCNJ1KCNH2MAPTNOTUMF2 | |
| SCHEMBL8485436 | 0.62 | KCNJ1 (0.66) | KCNJ1MAPTNOTUMF2ALDH1A1 | |
| SCHEMBL1811649 | 0.62 | LMNA (0.46) | MAPTALDH1A1LMNAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726195-A | Aminoacyl adenylate mimics as novel antimicrobial and antiparasitic agents | CUBIST PHARMACEUTICALS, INC. (US) | 1998-03-10 | — | — | US | disclosed |