Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542422 | 0.82 | PARP1 (0.36) | MEN1KMT2AKCNK3KCNK9POLB | |
| SCHEMBL8538025 | 0.77 | ITGB3 (0.49) | — | |
| SCHEMBL8537884 | 0.76 | SMN1; SMN2 (0.50) | KMT2APOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8540372 | 0.76 | KCNK3 (0.37) | MEN1KMT2AKCNK3KCNK9POLB | |
| SCHEMBL8538564 | 0.75 | PARP1 (0.40) | MEN1KMT2AKCNK3KCNK9POLB | |
| SCHEMBL5210059 | 0.72 | KMT2A (0.62) | MEN1KMT2AKCNK3KCNK9NPC1 | |
| Benzene SCHEMBL15881255 | 0.72 | HSD17B10 (0.67) | MEN1KMT2AKCNK3KCNK9POLB | |
| SCHEMBL4795890 | 0.72 | KMT2A (0.66) | MEN1KMT2APOLBNPC1RAB9A | |
| Urea SCHEMBL307661 | 0.71 | KMT2A (0.60) | MEN1KMT2AKCNK3KCNK9NPC1 | |
| SCHEMBL19704269 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2APOLBSMN1; SMN2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |