Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.49 |
| ▸ | ITGAV | P06756 | 15/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.41 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537899 | 0.85 | ITGB3 (0.49) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8541012 | 0.85 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8537884 | 0.78 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL8539600 | 0.77 | MEN1 (0.44) | — | |
| SCHEMBL7753126 | 0.77 | ADRA2A (0.58) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| Hydrochloric Acid SCHEMBL7562956 | 0.75 | ADRA2A (0.57) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8538020 | 0.74 | ITGB3 (0.57) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8538632 | 0.73 | ITGB3 (0.51) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8542422 | 0.72 | PARP1 (0.36) | — | |
| SCHEMBL8538084 | 0.72 | ITGB3 (0.47) | ITGB3ITGAVITGA2BITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |