Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.50 |
| ▸ | FABP3 | P05413 | 6/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538135 | 0.99 | FABP4 (0.49) | FABP4FABP3ADRA1ACSNK1A1TYRO3 | |
| SCHEMBL8541110 | 0.99 | FABP4 (0.49) | FABP4FABP3ADRA1ACSNK1A1TYRO3 | |
| SCHEMBL8537242 | 0.86 | PPARG (0.46) | ADRA1ACSNK1A1TYRO3DYRK1BALDH1A1 | |
| SCHEMBL8542537 | 0.83 | POLB (0.55) | ADRA1ACSNK1A1TYRO3DYRK1BALDH1A1 | |
| SCHEMBL8538155 | 0.83 | PDK2 (0.44) | ADRA1ACSNK1A1TYRO3DYRK1BTBXAS1 | |
| SCHEMBL8615627 | 0.81 | ADRA1A (0.53) | ADRA1ACSNK1A1TYRO3DYRK1BTP53 | |
| SCHEMBL8538145 | 0.80 | ADRA1A (0.52) | ADRA1ACSNK1A1TYRO3DYRK1BTP53 | |
| SCHEMBL8541667 | 0.80 | ADRA1A (0.52) | ADRA1ACSNK1A1TYRO3DYRK1BTP53 | |
| SCHEMBL8537029 | 0.77 | ADRA1A (0.50) | ADRA1ACSNK1A1TYRO3DYRK1BALDH1A1 | |
| SCHEMBL8660737 | 0.77 | KDM4E (0.62) | FABP4FABP3ALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |