Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24208239 | 0.74 | ALDH1A1 (0.46) | MAPTMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL22651703 | 0.74 | ALDH1A1 (0.46) | MAPTMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL3682182 | 0.66 | NQO2 (0.50) | NQO2MAPTMEN1NPC1KMT2A | |
| SCHEMBL8820259 | 0.66 | NQO2 (0.50) | NQO2MAPTMEN1NPC1KMT2A | |
| SCHEMBL10455960 | 0.63 | ALDH1A1 (0.52) | MAPTMEN1NPC1KMT2APOLB | |
| SCHEMBL14337206 | 0.62 | FAAH (0.40) | NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL3363930 | 0.62 | TOP2A (0.39) | NQO2MAPTMEN1NPC1KMT2A | |
| SCHEMBL3363928 | 0.62 | TOP2A (0.39) | NQO2MAPTMEN1NPC1KMT2A | |
| SCHEMBL4612924 | 0.61 | MAPT (0.79) | NQO2MAPTMEN1NPC1KMT2A | |
| SCHEMBL13156546 | 0.61 | MAPT (0.79) | NQO2MAPTMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763442-A | PHENAZINE AS ANTIMALERIA AGENTS | UNIVERSITEIT VAN PRETORIA (ZA) | 1998-06-09 | — | — | US | disclosed |