Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538325 | 0.73 | KCNJ1 (0.41) | KCNJ1KCNH2MAPTNOTUMF2 | |
| SCHEMBL8532934 | 0.73 | FBP1 (0.39) | KCNJ1KCNH2MAPTALDH1A1 | |
| SCHEMBL15177264 | 0.73 | MEN1 (0.46) | KCNH2MAPTALDH1A1LMNATDP1 | |
| SCHEMBL1269000 | 0.71 | KCNJ1 (0.68) | KCNJ1KCNH2MAPTNOTUMF2 | |
| SCHEMBL8539025 | 0.70 | KMT2A (0.34) | MAPTALDH1A1LMNATDP1POLB | |
| SCHEMBL12208232 | 0.70 | DRD5 (0.40) | MAPTALDH1A1TDP1POLBHTT | |
| SCHEMBL12208052 | 0.70 | MMP2 (0.43) | MAPTALDH1A1LMNATDP1HTT | |
| SCHEMBL8538202 | 0.68 | CYP2A6 (0.32) | — | |
| SCHEMBL12615985 | 0.66 | NOTUM (0.78) | KCNJ1MAPTNOTUMF2ALDH1A1 | |
| SCHEMBL15177266 | 0.64 | KMT2A (0.40) | MAPTALDH1A1LMNATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726195-A | Aminoacyl adenylate mimics as novel antimicrobial and antiparasitic agents | CUBIST PHARMACEUTICALS, INC. (US) | 1998-03-10 | — | — | US | disclosed |