Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536782 | 0.88 | NPC1 (0.37) | PARP1PARP10PARP15NPC1RAB9A | |
| SCHEMBL8544132 | 0.88 | LMNA (0.39) | PARP1PARP10PARP15NPC1RAB9A | |
| SCHEMBL8542355 | 0.87 | MAPT (0.42) | NPC1RAB9ASMN1; SMN2MITFKCNK3 | |
| SCHEMBL8538381 | 0.85 | PARP1 (0.38) | PARP1PARP10PARP15NPC1RAB9A | |
| SCHEMBL8538801 | 0.81 | KDR (0.37) | PARP1PARP10PARP15NPC1RAB9A | |
| SCHEMBL8539597 | 0.81 | MEN1 (0.41) | PARP1PARP10PARP15NPC1RAB9A | |
| SCHEMBL8542380 | 0.80 | PARP1 (0.37) | PARP1PARP10PARP15NPC1RAB9A | |
| SCHEMBL8540539 | 0.79 | PARP1 (0.41) | PARP1PARP10PARP15PARP14ALDH1A1 | |
| SCHEMBL8539103 | 0.79 | RXFP1 (0.41) | PARP1PARP10PARP15NPC1RAB9A | |
| SCHEMBL8542521 | 0.73 | CBS (0.37) | PARP1PARP10PARP15NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |