Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542422 | 0.93 | PARP1 (0.36) | PARP1MEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL8539554 | 0.89 | CA1 (0.38) | PARP1MEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL8540372 | 0.88 | KCNK3 (0.37) | PARP1MEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL8542364 | 0.87 | CES2 (0.47) | PARP1MEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL8536787 | 0.86 | PARP1 (0.40) | PARP1MEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL8538094 | 0.86 | CES2 (0.42) | PARP1MEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL8544139 | 0.86 | KAT6A (0.38) | PARP1MAPTMAPK1SMN1; SMN2PARP15 | |
| SCHEMBL8538385 | 0.85 | KCNK3 (0.43) | PARP1MEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL8542528 | 0.82 | SMN1; SMN2 (0.34) | PARP1MEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL8538807 | 0.80 | KCNK3 (0.42) | MEN1KMT2AKCNK3KCNK9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |